Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.33 |
| ▸ | CA9 | Q16790 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.32 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975481 | 0.88 | HDAC1 (0.36) | HDAC1HDAC2HDAC3TNFRSF1AABL1 | |
| SCHEMBL7975083 | 0.84 | CA12 (0.39) | HSD17B10ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL7931191 | 0.84 | HDAC1 (0.35) | HDAC1HDAC2HDAC3ALDH1A1TNFRSF1A | |
| SCHEMBL7931232 | 0.81 | HDAC2 (0.35) | HDAC1HDAC2HDAC3MAPTTSHR | |
| SCHEMBL7934057 | 0.80 | SLC6A3 (0.40) | ALDH1A1MAPTCA12CA9LMNA | |
| SCHEMBL7969052 | 0.79 | CA12 (0.42) | ALDH1A1MAPK1CA12CA9CA2 | |
| SCHEMBL7934163 | 0.79 | KDM4E (0.45) | ALDH1A1MAPTCA12CA9CA2 | |
| SCHEMBL7969353 | 0.79 | SLC6A3 (0.40) | ALDH1A1MAPTCA12CA9CA2 | |
| SCHEMBL7969661 | 0.78 | PTGDR2 (0.41) | CA12CA9CA2LMNA | |
| SCHEMBL7922070 | 0.78 | L3MBTL1 (0.35) | ALDH1A1MAPTTSHRCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |