Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | TNFRSF1A | P19438 | 3/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969815 | 0.88 | HDAC1 (0.36) | HDAC1HDAC2HDAC3SLC6A7ABL1 | |
| SCHEMBL7971921 | 0.86 | CTSL (0.32) | PTGDR2 | |
| SCHEMBL7929501 | 0.83 | MCL1 (0.39) | PTGDR2 | |
| SCHEMBL7971803 | 0.83 | PGR (0.36) | HDAC1HDAC2HDAC3SLC6A7TNFRSF1A | |
| SCHEMBL7972143 | 0.78 | PGR (0.36) | HDAC1HDAC2HDAC3SLC6A7DAO | |
| SCHEMBL7931169 | 0.78 | CA12 (0.39) | PTGDR2 | |
| SCHEMBL7974920 | 0.77 | BCL2L1 (0.39) | HDAC1HDAC2HDAC3PTGDR2 | |
| SCHEMBL7970423 | 0.76 | HAO1 (0.35) | — | |
| SCHEMBL5209382 | 0.76 | CCR5 (0.41) | HDAC1HDAC2HDAC3TNFRSF1A | |
| SCHEMBL3499284 | 0.76 | ALAD (0.35) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |