Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972855 | 0.96 | PTGES (0.40) | PTGESALOX5PPARGCTSKCA1 | |
| SCHEMBL7064266 | 0.91 | CA1 (0.41) | PTGESALOX5PPARGCTSKCA1 | |
| SCHEMBL7972991 | 0.89 | ALDH1A1 (0.41) | CA1CA2CA9LMNAALDH1A1 | |
| SCHEMBL7973318 | 0.85 | ALDH1A1 (0.42) | CA1CA2CA9LMNAALDH1A1 | |
| SCHEMBL7976065 | 0.82 | ALDH1A1 (0.39) | LMNAALDH1A1TSHRKDM4EUSP2 | |
| SCHEMBL7971433 | 0.82 | FKBP1A (0.38) | PTGESALOX5PPARGCTSKCA1 | |
| SCHEMBL7973259 | 0.80 | FKBP1A (0.43) | PTGESALOX5PPARGCTSKCA1 | |
| SCHEMBL7064408 | 0.80 | ALDH1A1 (0.44) | CA1CA2CA9HCAR2LMNA | |
| SCHEMBL7959907 | 0.79 | TDP1 (0.41) | PTGESALOX5PPARGLMNAALDH1A1 | |
| SCHEMBL7973451 | 0.78 | CA1 (0.38) | PTGESALOX5PPARGCTSKCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |