Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CTRC | Q99895 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973318 | 0.96 | ALDH1A1 (0.42) | ALDH1A1CTRCTSHRMAPK1TDP1 | |
| SCHEMBL7064408 | 0.91 | ALDH1A1 (0.44) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL7970070 | 0.89 | PTGES (0.40) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL7972855 | 0.85 | PTGES (0.40) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL7976065 | 0.84 | ALDH1A1 (0.39) | ALDH1A1CTRCTSHRMAPK1TDP1 | |
| SCHEMBL16979054 | 0.83 | CA1 (0.47) | ALDH1A1CTRCTSHRMAPK1TDP1 | |
| SCHEMBL31479931 | 0.82 | DPP8 (0.41) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 | |
| SCHEMBL7976230 | 0.81 | CTRC (0.38) | ALDH1A1CTRCTSHRMAPK1TDP1 | |
| SCHEMBL14143485 | 0.81 | LMNA (0.49) | ALDH1A1MAPK1TDP1L3MBTL1LMNA | |
| SCHEMBL7959907 | 0.80 | TDP1 (0.41) | ALDH1A1TSHRMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172234-B1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-09 | — | — | US | disclosed |
| EP-0976729-A1 | Optically active cyclic amino acid ester derivatives and processes for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-02-02 | — | — | EP | disclosed |