Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7929501 | 0.87 | MCL1 (0.39) | MCL1DHODHCCR5 | |
| SCHEMBL7922070 | 0.87 | L3MBTL1 (0.35) | HAO1ADORA3 | |
| SCHEMBL7929430 | 0.87 | PTGS2 (0.36) | CCR5 | |
| SCHEMBL7974920 | 0.86 | BCL2L1 (0.39) | — | |
| SCHEMBL7929484 | 0.85 | CCR5 (0.32) | CCR5 | |
| SCHEMBL3499284 | 0.85 | ALAD (0.35) | — | |
| SCHEMBL7929550 | 0.84 | RXRA (0.37) | DHODH | |
| SCHEMBL7931034 | 0.84 | MAPT (0.41) | DHODH | |
| SCHEMBL7931169 | 0.84 | CA12 (0.39) | DHODHMMP2MMP9CCR5 | |
| SCHEMBL7972312 | 0.84 | CCR5 (0.38) | MCL1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |