Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.39 |
| ▸ | BAD | Q92934 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.34 |
| ▸ | HAO2 | Q9NYQ3 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | GALR1 | P47211 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | RPA1 | P27694 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499284 | 0.88 | ALAD (0.35) | CA12PTGDR2GALR1ALPL | |
| SCHEMBL7929501 | 0.88 | MCL1 (0.39) | CA12CA9PTGDR2SMN1; SMN2GALR1 | |
| SCHEMBL7934175 | 0.87 | PTGDR2 (0.43) | CA12CA9PTGDR2HDAC2GALR1 | |
| SCHEMBL7970423 | 0.86 | HAO1 (0.35) | — | |
| SCHEMBL7931034 | 0.85 | MAPT (0.41) | CA12CA9SMN1; SMN2ALPLKMT2A | |
| SCHEMBL7929550 | 0.85 | RXRA (0.37) | — | |
| SCHEMBL7934057 | 0.85 | SLC6A3 (0.40) | CA12CA9KDM4ESMN1; SMN2KMT2A | |
| SCHEMBL7931169 | 0.85 | CA12 (0.39) | CA12CA9PTGDR2 | |
| SCHEMBL7972312 | 0.85 | CCR5 (0.38) | CA12CA9PTGDR2GALR1ALPL | |
| SCHEMBL7929538 | 0.84 | CA12 (0.43) | CA12CA9PTGDR2GALR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235771-B1 | AIDS THERPAY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |