Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.52 |
| ▸ | HTR7 | P34969 | 4/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | SOD1 | P00441 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | THRA | P10827 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981292 | 0.87 | HSD11B1 (0.49) | HTR1AHTR7HSD11B1SOD1ALDH1A1 | |
| SCHEMBL7980861 | 0.86 | ACHE (0.53) | HTR1AHTR7HSD11B1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6599700 | 0.84 | HTR1A (0.62) | HTR1AHTR7HTR2AHTR2CKMT2A | |
| Hydrochloric Acid SCHEMBL6599492 | 0.82 | HTR1A (0.66) | HTR1AHTR7DRD2HTR2AHTR2C | |
| SCHEMBL7984579 | 0.76 | ACHE (0.52) | HTR1AHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL7984156 | 0.75 | HSD11B1 (0.61) | HSD11B1MEN1KMT2ATHRBALDH1A1 | |
| Hydrochloric Acid SCHEMBL5364551 | 0.75 | ACHE (0.51) | HTR1AHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL7970723 | 0.75 | ACHE (0.51) | HTR1AHTR7MEN1KMT2AALDH1A1 | |
| SCHEMBL14578069 | 0.74 | KMT2A (0.51) | DRD2HTR2AMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL5360736 | 0.74 | ACHE (0.50) | HTR1AHTR7MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |