Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HTR1D | P28221 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SOD1 | P00441 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7980861 | 0.87 | ACHE (0.53) | HSD11B1ALDH1A1PRNPRXFP1HTR1A | |
| SCHEMBL7970936 | 0.87 | HTR1A (0.52) | HSD11B1ALDH1A1HTR1AHTR7SOD1 | |
| Hydrochloric Acid SCHEMBL6599700 | 0.83 | HTR1A (0.62) | L3MBTL1ALDH1A1HTR1AMAPTHTR1D | |
| Hydrochloric Acid SCHEMBL6599492 | 0.81 | HTR1A (0.66) | ALDH1A1HTR1AMAPTHTR1DHTR7 | |
| SCHEMBL7984156 | 0.78 | HSD11B1 (0.61) | HSD11B1L3MBTL1ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL4834908 | 0.76 | HSD11B1 (0.62) | HSD11B1ALDH1A1CYP1A2CYP2C9HSD17B10 | |
| SCHEMBL7984579 | 0.76 | ACHE (0.52) | ALDH1A1HTR1AKDM4EPOLBHTR7 | |
| Hydrochloric Acid SCHEMBL5364551 | 0.75 | ACHE (0.51) | ALDH1A1HTR1AKDM4EPOLBHTR7 | |
| SCHEMBL7970723 | 0.75 | ACHE (0.51) | ALDH1A1HTR1AKDM4EHTR7TSHR | |
| SCHEMBL14578069 | 0.74 | KMT2A (0.51) | ALDH1A1HSD17B10KDM4EPOLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007431-A2 | BENZOTHIOPHENE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-02-01 | — | — | WO | disclosed |