Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971422 | 0.84 | RAB9A (0.48) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL7961051 | 0.82 | ALDH1A1 (0.37) | L3MBTL1POLBLMNAALDH1A1MEN1 | |
| SCHEMBL7977541 | 0.82 | CYP4F2 (0.35) | TSHRALDH1A1CYP1A2CYP3A4MEN1 | |
| SCHEMBL7974447 | 0.79 | CYP4F2 (0.43) | L3MBTL1POLBLMNAALDH1A1CYP3A4 | |
| SCHEMBL7694058 | 0.66 | GLA (0.65) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL7908984 | 0.65 | L3MBTL1 (0.67) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL8972353 | 0.65 | L3MBTL1 (0.67) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL474080 | 0.65 | L3MBTL1 (0.67) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL8973343 | 0.65 | L3MBTL1 (0.67) | RAB9AL3MBTL1POLBTSHRLMNA | |
| SCHEMBL8971856 | 0.65 | L3MBTL1 (0.67) | RAB9AL3MBTL1POLBTSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |