Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 6/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971522 | 0.83 | CCR3 (0.50) | — | |
| Hydrochloric Acid SCHEMBL7974723 | 0.82 | CCR3 (0.49) | — | |
| Hydrochloric Acid SCHEMBL7977428 | 0.79 | SIGMAR1 (0.52) | MEN1KMT2ADRD2 | |
| SCHEMBL7971195 | 0.76 | KCNH2 (0.56) | DRD2DRD3ADRA1B | |
| SCHEMBL7977198 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL7961134 | 0.71 | HCAR2 (0.31) | — | |
| SCHEMBL6617019 | 0.71 | DRD2 (0.62) | MEN1KMT2AP2RX7DRD2DRD3 | |
| SCHEMBL7383823 | 0.71 | DRD2 (0.66) | ALDH1A1L3MBTL1P2RX7DRD2DRD3 | |
| SCHEMBL11938950 | 0.71 | OPRM1 (0.68) | P2RX7DRD2DRD3ADRA1B | |
| SCHEMBL7974371 | 0.71 | HTR1A (0.48) | ALDH1A1L3MBTL1MEN1KMT2ADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| EP-0968164-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| WO-1998033758-A1 | BICYCLIC QUINONE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-08-06 | — | — | WO | disclosed |