Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7971928 | 0.99 | SIGMAR1 (0.45) | SIGMAR1FAAHCHRM3L3MBTL1 | |
| SCHEMBL7973164 | 0.97 | SIGMAR1 (0.49) | SIGMAR1FAAH | |
| Hydrochloric Acid SCHEMBL7983443 | 0.96 | SIGMAR1 (0.48) | SIGMAR1FAAH | |
| SCHEMBL7987161 | 0.89 | SMYD2 (0.42) | SIGMAR1FAAH | |
| Hydrochloric Acid SCHEMBL7971940 | 0.89 | SMYD2 (0.41) | SIGMAR1FAAH | |
| SCHEMBL7985583 | 0.87 | ALDH1A1 (0.43) | SIGMAR1FAAH | |
| SCHEMBL7972040 | 0.87 | SIGMAR1 (0.40) | SIGMAR1FAAH | |
| SCHEMBL7984736 | 0.86 | SMYD2 (0.46) | — | |
| Hydrochloric Acid SCHEMBL7982606 | 0.86 | FAAH (0.39) | SIGMAR1FAAH | |
| Hydrochloric Acid SCHEMBL7983892 | 0.86 | ALDH1A1 (0.42) | SIGMAR1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |