Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | PTAFR | P25105 | 1/20 | 0.33 |
| ▸ | F13A1 | P00488 | 1/20 | 0.33 |
| ▸ | TGM2 | P21980 | 1/20 | 0.33 |
| ▸ | TGM1 | P22735 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7989621 | 0.99 | FAAH (0.36) | FAAHSIGMAR1DRD4PTPN2PTPN1 | |
| SCHEMBL7972040 | 0.88 | SIGMAR1 (0.40) | FAAHSIGMAR1DRD4KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7982606 | 0.87 | FAAH (0.39) | FAAHSIGMAR1DRD4KDM4EALDH1A1 | |
| SCHEMBL7985583 | 0.86 | ALDH1A1 (0.43) | FAAHSIGMAR1DRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7983892 | 0.85 | ALDH1A1 (0.42) | FAAHSIGMAR1DRD4ALDH1A1 | |
| SCHEMBL7987161 | 0.84 | SMYD2 (0.42) | FAAHSIGMAR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7971940 | 0.83 | SMYD2 (0.41) | FAAHSIGMAR1KDM4EALDH1A1 | |
| SCHEMBL7982426 | 0.83 | LTA4H (0.47) | DRD4ALDH1A1GRIN2B | |
| SCHEMBL7973164 | 0.83 | SIGMAR1 (0.49) | FAAHSIGMAR1KDM4EALDH1A1ALOX15 | |
| Hydrochloric Acid SCHEMBL7983443 | 0.83 | SIGMAR1 (0.48) | FAAHSIGMAR1KDM4EALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |