Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.52 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.50 |
| ▸ | MMP9 | P14780 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4504076 | 0.85 | CYP19A1 (0.83) | LMNACYP19A1ALDH1A1GAAMAPT | |
| SCHEMBL6478175 | 0.81 | LMNA (0.62) | LMNACYP19A1ALDH1A1GAAHPGD | |
| SCHEMBL28272081 | 0.80 | LMNA (0.65) | LMNACYP19A1ALDH1A1GAAHPGD | |
| SCHEMBL7970997 | 0.78 | CXCR4 (0.69) | LMNAALDH1A1HPGDSMN1; SMN2GRIN1 | |
| SCHEMBL6476661 | 0.77 | LMNA (0.70) | LMNACYP19A1ALDH1A1HPGD | |
| SCHEMBL18052431 | 0.76 | LMNA (0.62) | LMNACYP19A1ALDH1A1GAAHPGD | |
| SCHEMBL7827745 | 0.75 | MMP1 (0.62) | LMNACYP19A1ALDH1A1GAAHPGD | |
| SCHEMBL18114379 | 0.75 | MMP1 (0.62) | LMNACYP19A1ALDH1A1GAAHPGD | |
| SCHEMBL7973291 | 0.75 | OPRK1 (0.65) | LMNACYP19A1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL10487816 | 0.74 | CYP19A1 (0.74) | LMNACYP19A1ALDH1A1MAPTSLC12A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |