Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 7/20 | 0.47 |
| ▸ | REN | P00797 | 2/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.44 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7697541 | 0.86 | CTSK (0.57) | CTSKACE2 | |
| SCHEMBL6332850 | 0.86 | CTSK (0.57) | CTSKACE2 | |
| SCHEMBL7173287 | 0.82 | PSEN1 (0.57) | CTSKRENPSEN1PSEN2APH1B | |
| SCHEMBL892964 | 0.82 | PSEN1 (0.57) | CTSKRENPSEN1PSEN2APH1B | |
| SCHEMBL3324393 | 0.81 | LTA4H (0.49) | RENANPEPLTA4H | |
| SCHEMBL7967827 | 0.79 | CTSK (0.48) | CTSK | |
| SCHEMBL7967830 | 0.79 | CTSK (0.48) | CTSK | |
| Cadaverine Tartrate SCHEMBL9016048 | 0.77 | REN (0.48) | CTSKRENANPEPLTA4HCSNK1E | |
| SCHEMBL7278549 | 0.76 | CAPN1 (0.59) | — | |
| SCHEMBL7278543 | 0.76 | CAPN1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001012599-A1 | NEW ETHYLAZIRIDINE DERIVATIVES AND THEIR PREPARATION METHODS | SAMCHULLY PHARM CO., LTD. (KR) | 2001-02-22 | — | — | WO | disclosed |