Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 2/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 8/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973961 | 1.00 | RAB9A (0.44) | RAB9AMAPTMEN1KMT2ASENP6 | |
| SCHEMBL7989236 | 0.88 | CYP1A2 (0.48) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7989237 | 0.88 | CYP1A2 (0.48) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6784562 | 0.85 | SENP6 (0.56) | RAB9AMAPTMEN1KMT2ASENP6 | |
| SCHEMBL6784565 | 0.85 | SENP6 (0.56) | RAB9AMAPTMEN1KMT2ASENP6 | |
| SCHEMBL7987392 | 0.82 | NPC1 (0.40) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7987387 | 0.82 | NPC1 (0.40) | RAB9AMAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7984107 | 0.76 | ALDH1A1 (0.32) | MAPTGAAALDH1A1 | |
| SCHEMBL7985243 | 0.71 | TDP1 (0.34) | MEN1KMT2A | |
| SCHEMBL11279464 | 0.67 | RAB9A (0.72) | RAB9AMAPTMEN1KMT2ASENP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6319924-B1 | FOR THERAPY OF DELETERIOUS MENTAL STATES | MERCK SHARP & DOHME LTD. (GB) | 2001-11-20 | — | — | US | disclosed |