SCHEMBL7974002

SCHEMBL7974002

Clc1cnc2ccc[c]c2n1

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
GPR3 P46089 1/20 0.31
HTT P42858 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
PDE10A Q9Y233 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7976285 0.85 ALDH1A1 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1
SCHEMBL4848335 0.77 NCF1 (0.32) ALDH1A1NPC1RAB9AKDM4EGPR3
SCHEMBL7271710 0.77 CYP1A2 (0.37) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL9601037 0.74 TDP1 (0.52) TDP1KDM4EL3MBTL1
SCHEMBL3569692 0.73 HTT (0.41) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL30731286 0.70 SMN1; SMN2 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1
SCHEMBL222284 0.70 SMN1; SMN2 (0.53) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1
SCHEMBL4851470 0.69 CYP3A4 (0.30)
SCHEMBL31311 0.69 MAPT (0.39) ALDH1A1KDM4E
Hydrogen Sulfide SCHEMBL28270010 0.69 SMN1; SMN2 (0.52) ALDH1A1NPC1RAB9ASMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed