SCHEMBL9601037

SCHEMBL9601037

Clc1nc2[c]cccc2nc1Cl

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.52
KDM4E B2RXH2 1/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
MAPT P10636 1/20 0.31
HTR3B O95264 1/20 0.30
HTR3A P46098 1/20 0.30
HRH4 Q9H3N8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25712 0.77 MAPT (0.52) TDP1KDM4EKMT2AL3MBTL1MAOA
SCHEMBL4573051 0.74 GPR3 (0.39) KDM4EL3MBTL1MAPTHRH4
SCHEMBL7974002 0.74 ALDH1A1 (0.37) TDP1KDM4EL3MBTL1
SCHEMBL7976285 0.74 ALDH1A1 (0.37) TDP1
SCHEMBL2217686 0.72 BCHE (0.30) KDM4E
SCHEMBL29451077 0.70 TDP1 (1.00) TDP1KDM4EPKMKMT2AL3MBTL1
SCHEMBL116696 0.70 TDP1 (1.00) TDP1KDM4EPKMKMT2AL3MBTL1
SCHEMBL655231 0.69 MYC (0.38) TDP1KDM4EKMT2AL3MBTL1MAOA
SCHEMBL7271710 0.65 CYP1A2 (0.37) KDM4EPKMKMT2AHTR3AHRH4
SCHEMBL4848335 0.65 NCF1 (0.32) KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0114031-B2 PREPARATION PROCESS OF STORAGE-STABLE AQUEOUS SOLUTIONS OF WATER-SOLUBLE REACTIVE DYES CIBA-GEIGY AG (CH) 1993-01-20 EP disclosed
EP-0114031-B1 PREPARATION PROCESS OF STORAGE-STABLE AQUEOUS SOLUTIONS OF WATER-SOLUBLE REACTIVE DYES CIBA-GEIGY AG (CH) 1986-10-08 EP disclosed
US-4523924-A Process for the preparation of stable aqueous solutions of water-soluble reactive dyes by membrane separation CIBA-GEIGY CORPORATION (US) 1985-06-18 US disclosed
EP-0062865-B1 DYEING PROCESS BAYER AG (DE) 1985-02-13 EP disclosed
EP-0114031-A2 Preparation process of storage-stable aqueous solutions of water-soluble reactive dyes CIBA-GEIGY AG (CH) 1984-07-25 EP disclosed
EP-0062865-A1 Dyeing process BAYER AG (DE) 1982-10-20 EP disclosed
US-3990841-A Sulfinic acid and thiourea dyeing of cellulosic textiles PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1976-11-09 US disclosed