Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7974248 | 0.76 | SMN1; SMN2 (0.41) | SMN1; SMN2GAAKDM4EMAPK1ALDH1A1 | |
| SCHEMBL7987930 | 0.76 | KMT2A (0.57) | SMN1; SMN2KDM4EHTTRAB9AALDH1A1 | |
| SCHEMBL7974138 | 0.74 | KMT2A (0.52) | SMN1; SMN2GAAKDM4EHTTRAB9A | |
| SCHEMBL7987837 | 0.73 | RECQL (0.47) | SMN1; SMN2GAAKDM4EHTTMAPK1 | |
| SCHEMBL7991565 | 0.72 | TSHR (0.49) | SMN1; SMN2GAAKDM4EHTTMAPK1 | |
| SCHEMBL7985495 | 0.71 | CYP11B1 (0.39) | SMN1; SMN2RAB9AJAK2LMNATSHR | |
| SCHEMBL7984433 | 0.70 | SMN1; SMN2 (0.47) | AURKASMN1; SMN2KDM4EHTTALDH1A1 | |
| SCHEMBL7987938 | 0.69 | KDM4E (0.44) | KDM4ERAB9AALDH1A1LMNA | |
| SCHEMBL7988641 | 0.69 | KMT2A (0.44) | SMN1; SMN2GAAKDM4ERAB9AALDH1A1 | |
| SCHEMBL7974324 | 0.68 | TNF (0.44) | SMN1; SMN2KDM4EHTTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |