Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987961 | 0.89 | MAPT (0.47) | CYP11B1CYP11B2KMT2AMAPK8MAPT | |
| SCHEMBL7973987 | 0.88 | FGFR1 (0.45) | CYP11B1CYP11B2FGFR1FGFR4KMT2A | |
| SCHEMBL7991565 | 0.84 | TSHR (0.49) | FGFR1FGFR4KMT2ATSHRHSD17B10 | |
| SCHEMBL7991814 | 0.83 | HSP90AA1 (0.44) | KMT2AMAPTMEN1SMN1; SMN2POLB | |
| SCHEMBL7974324 | 0.81 | TNF (0.44) | KMT2AMAPTTSHRMEN1HSD17B10 | |
| SCHEMBL7985508 | 0.81 | ALDH1A1 (0.43) | KMT2AMEN1SMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7987598 | 0.81 | RIOK2 (0.41) | FGFR1FGFR4KMT2AMAPK8MEN1 | |
| SCHEMBL7985670 | 0.81 | CDK9 (0.42) | KMT2AMAPK8MAPTYTHDC1LMNA | |
| SCHEMBL7974162 | 0.81 | KDM4E (0.52) | FGFR1FGFR4KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7988382 | 0.80 | KMT2A (0.41) | KMT2ATSHRMEN1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |