Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7987938 | 0.87 | KDM4E (0.44) | LMNAL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7974324 | 0.86 | TNF (0.44) | SMN1; SMN2LMNAHTTL3MBTL1KMT2A | |
| SCHEMBL7991817 | 0.85 | KDM4E (0.51) | SMN1; SMN2LMNAHTTL3MBTL1CYP11B1 | |
| SCHEMBL7991565 | 0.84 | TSHR (0.49) | SMN1; SMN2LMNAHTTL3MBTL1KMT2A | |
| SCHEMBL7973987 | 0.81 | FGFR1 (0.45) | SMN1; SMN2LMNAHTTCYP11B1CYP11B2 | |
| SCHEMBL7988641 | 0.81 | KMT2A (0.44) | SMN1; SMN2LMNACYP11B1CYP11B2KMT2A | |
| SCHEMBL7987961 | 0.80 | MAPT (0.47) | LMNACYP11B1CYP11B2KMT2AAURKA | |
| SCHEMBL9714613 | 0.79 | CYP11B1 (0.50) | SMN1; SMN2LMNACYP11B1CYP11B2KMT2A | |
| SCHEMBL7987598 | 0.79 | RIOK2 (0.41) | SMN1; SMN2L3MBTL1KMT2AMEN1MAPK8 | |
| SCHEMBL7987930 | 0.79 | KMT2A (0.57) | SMN1; SMN2LMNAHTTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |