Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | PARN | O95453 | 1/20 | 0.41 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | VSIR | Q9H7M9 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.34 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.34 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988795 | 0.93 | BRD4 (0.40) | BRD4PARNCNOT7PAX8KAT8 | |
| SCHEMBL7985482 | 0.91 | PAX8 (0.43) | BRD4PARNCNOT7P2RX7HPGD | |
| SCHEMBL7974152 | 0.87 | HPGD (0.47) | BRD4PARNCNOT7HPGDMCL1 | |
| SCHEMBL7984762 | 0.83 | P2RX7 (0.45) | PARNCNOT7P2RX7HPGDALDH1A1 | |
| SCHEMBL7984731 | 0.82 | ABCC8 (0.39) | BRD4PARNCNOT7PAX8KAT8 | |
| SCHEMBL7988789 | 0.80 | BRD4 (0.40) | BRD4HPGDPAX8ALDH1A1SMN1; SMN2 | |
| SCHEMBL7984489 | 0.78 | P2RX7 (0.45) | PARNCNOT7P2RX7HPGDALDH1A1 | |
| SCHEMBL7988597 | 0.78 | PARN (0.48) | PARNCNOT7P2RX7HPGDALDH1A1 | |
| SCHEMBL7985342 | 0.78 | CNOT7 (0.51) | PARNCNOT7HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL7985460 | 0.78 | CNOT7 (0.45) | PARNCNOT7P2RX7HPGDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |