Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | PARN | O95453 | 1/20 | 0.36 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988753 | 0.90 | ACP1 (0.41) | ACP1P2RX7PDE4APDE4BPDE4C | |
| SCHEMBL7985415 | 0.89 | ALDH1A1 (0.39) | P2RX7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7987224 | 0.88 | LMNA (0.44) | P2RX7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7984682 | 0.88 | PDE4A (0.39) | P2RX7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7974015 | 0.86 | PARN (0.49) | ACP1IDO1CXCR2ALDH1A1PARN | |
| SCHEMBL7988784 | 0.86 | MAPK1 (0.43) | ACP1IDO1CXCR2LMNAPARN | |
| SCHEMBL7988416 | 0.85 | ALDH1A1 (0.49) | P2RX7ALDH1A1 | |
| SCHEMBL7973628 | 0.84 | SMN1; SMN2 (0.48) | ACP1P2RX7IDO1CXCR2PARN | |
| SCHEMBL7986760 | 0.84 | ALDH1A1 (0.41) | ACP1P2RX7PDE4APDE4BPDE4C | |
| SCHEMBL7974198 | 0.84 | LMNA (0.41) | ACP1MAPTPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |