Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIOK2 | Q9BVS4 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ICMT | O60725 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 3/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.39 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.39 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.39 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991565 | 0.86 | TSHR (0.49) | KMT2AFGFR1FGFR4KDM4EHPGD | |
| SCHEMBL7988641 | 0.84 | KMT2A (0.44) | KMT2AMEN1GSK3AFGFR1FGFR4 | |
| SCHEMBL7987961 | 0.83 | MAPT (0.47) | KMT2AMAPK8ALDH1A1YTHDC1 | |
| SCHEMBL7992368 | 0.83 | TP53 (0.47) | KMT2AMEN1MAPK8RAB9AYTHDC1 | |
| SCHEMBL7973987 | 0.83 | FGFR1 (0.45) | KMT2AFGFR1FGFR4RAB9ASMN1; SMN2 | |
| SCHEMBL7985508 | 0.83 | ALDH1A1 (0.43) | KMT2AMEN1MAPK10L3MBTL1ALDH1A1 | |
| SCHEMBL7974162 | 0.83 | KDM4E (0.52) | KMT2AFGFR1FGFR4KDM4EL3MBTL1 | |
| SCHEMBL7985670 | 0.83 | CDK9 (0.42) | KMT2AMAPK8KDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7974223 | 0.82 | RAB9A (0.46) | RAB9AL3MBTL1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7986281 | 0.81 | KMT2A (0.39) | KMT2AFGFR1FGFR4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |