Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 2/20 | 0.38 |
| ▸ | RXRB | P28702 | 2/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7405031 | 0.85 | MAP3K7 (0.44) | KDM4ELMNACA1CA2MAP3K7 | |
| SCHEMBL7974225 | 0.83 | APP (0.36) | KDM4ELMNANR4A2MAP3K7TAB1 | |
| SCHEMBL8490705 | 0.81 | TRPA1 (0.38) | LMNANPC1POLBMAPK1MEN1 | |
| SCHEMBL2488026 | 0.80 | P2RX7 (0.32) | ALDH1A1KMT2A | |
| SCHEMBL8487037 | 0.79 | — | — | |
| SCHEMBL7978927 | 0.77 | AKR1C3 (0.42) | RXRARXRBNR4A2RXRGMAPT | |
| SCHEMBL1828996 | 0.76 | KDM4E (0.39) | KDM4ELMNAHCAR2TSHRSMN1; SMN2 | |
| SCHEMBL8585822 | 0.75 | GPR52 (0.35) | MAP3K7TAB1 | |
| SCHEMBL6821893 | 0.74 | ALDH1A1 (0.37) | KDM4EHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7782729 | 0.71 | HDAC3 (0.38) | KDM4ELMNAHDAC3TNKSHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001081317-A1 | CHIRAL IMIDAZOYL INTERMEDIATES FOR THE SYNTHESIS OF 2-(4-IMIDAZOYL)-CYCLOPROPYL DERIVATIVES | GLIATECH, INC. (US) | 2001-11-01 | — | — | WO | disclosed |