Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.35 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974197 | 0.78 | MRGPRX4 (0.51) | SMN1; SMN2PPARALTB4RLTB4R2MRGPRX4 | |
| SCHEMBL7522087 | 0.76 | WDR5 (0.43) | LTB4RLTB4R2MRGPRX4KDM4EALDH1A1 | |
| SCHEMBL23783073 | 0.74 | KDM4E (0.54) | KDM4EALDH1A1HPGDBRD4 | |
| SCHEMBL7972777 | 0.73 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARA | |
| SCHEMBL8935912 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARGPTPN1 | |
| SCHEMBL8935919 | 0.72 | SMN1; SMN2 (0.49) | SMN1; SMN2PPARAPPARGPTPN1 | |
| SCHEMBL7972644 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2PPARAPPARGBRD4 | |
| SCHEMBL7972678 | 0.69 | ALDH1A1 (0.45) | SMN1; SMN2PPARALTB4RMRGPRX4PPARG | |
| SCHEMBL4814937 | 0.69 | SMN1; SMN2 (0.74) | SMN1; SMN2PPARAPPARGTSHRPOLB | |
| SCHEMBL7962725 | 0.68 | SMN1; SMN2 (0.58) | SMN1; SMN2PPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |