Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC8 | Q09428 | 1/20 | 0.43 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | PARN | O95453 | 1/20 | 0.38 |
| ▸ | CNOT7 | Q9UIV1 | 1/20 | 0.38 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991403 | 0.90 | ABCC8 (0.43) | ABCC8KCNJ11SMN1; SMN2NR1H4PARN | |
| SCHEMBL7992270 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11ACP1NR1H4PARN | |
| SCHEMBL7974282 | 0.89 | ABCC8 (0.43) | ABCC8KCNJ11NR1H4PARNCNOT7 | |
| SCHEMBL7991600 | 0.89 | ACP1 (0.42) | GLAHTTUBE2NSMN1; SMN2L3MBTL1 | |
| SCHEMBL7974492 | 0.89 | ABCC8 (0.47) | ABCC8KCNJ11HTTSMN1; SMN2NR1H4 | |
| SCHEMBL7988017 | 0.89 | KDM4E (0.43) | ABCC8KCNJ11HTTSMN1; SMN2CXCR2 | |
| SCHEMBL7984474 | 0.89 | ABCC8 (0.42) | ABCC8KCNJ11NR1H4PARNCNOT7 | |
| SCHEMBL7973628 | 0.88 | SMN1; SMN2 (0.48) | GLAHTTUBE2NSMN1; SMN2L3MBTL1 | |
| SCHEMBL7974015 | 0.88 | PARN (0.49) | GLAHTTUBE2NSMN1; SMN2L3MBTL1 | |
| SCHEMBL7985602 | 0.88 | SERPINE1 (0.45) | ABCC8KCNJ11HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |