Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984889 | 0.90 | NPC1 (0.46) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7973841 | 0.88 | RAB9A (0.47) | HDAC1ALDH1A1RAB9ANPC1HDAC2 | |
| SCHEMBL7986413 | 0.87 | HTT (0.52) | HDAC1ALDH1A1RAB9ASMN1; SMN2HDAC2 | |
| SCHEMBL7984257 | 0.87 | RAB9A (0.48) | ALDH1A1RAB9ASMN1; SMN2NPC1LMNA | |
| SCHEMBL7992620 | 0.85 | NPC1 (0.53) | ALDH1A1RAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL7974172 | 0.85 | HDAC3 (0.44) | HDAC1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7985255 | 0.84 | ALDH1A1 (0.51) | HDAC1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7985361 | 0.82 | P2RY14 (0.52) | HDAC1ALDH1A1HDAC2KDM4E | |
| SCHEMBL7988677 | 0.81 | SMN1; SMN2 (0.51) | HDAC1ALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL7984455 | 0.81 | ABCB1 (0.54) | ALDH1A1SMN1; SMN2NPC1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |