Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985340 | 0.90 | NTRK1 (0.51) | ABCB1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL7992620 | 0.86 | NPC1 (0.53) | SMN1; SMN2ALDH1A1MEN1KMT2ASIRT2 | |
| SCHEMBL7984937 | 0.86 | ADORA3 (0.52) | ABCB1SMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7984889 | 0.83 | NPC1 (0.46) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7992368 | 0.82 | TP53 (0.47) | MEN1KMT2APOLBMAPT | |
| SCHEMBL7974555 | 0.81 | HDAC1 (0.45) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL7988637 | 0.81 | NPC1 (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7984257 | 0.80 | RAB9A (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2ASIRT2 | |
| SCHEMBL7974265 | 0.80 | MCHR1 (0.47) | SMN1; SMN2MEN1KMT2APOLBNPC1 | |
| SCHEMBL7988231 | 0.79 | NPC1 (0.47) | KMT2ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310070-B1 | FOR TREATING NEPHRITIS, IMPROVING PROTEINURIA DUE TO GLOMERULONEPHRITIS AND PREVENTING AGGRAVATION OF NEPHRITIS | JAPAN ENERGY CORPORATION (JP) | 2001-10-30 | — | — | US | disclosed |
| EP-0999211-A1 | NOVEL PURINE DERIVATIVES AND MEDICINAL USE THEREOF | JAPAN ENERGY CORPORATION (JP) | 2000-05-10 | — | — | EP | disclosed |