Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.54 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | APEX1 | P27695 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA3 | P07451 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31109058 | 1.00 | HCAR2 (0.54) | HCAR2NAMPTCHEK2ALDH1A1KDM4E | |
| SCHEMBL25213797 | 0.85 | HCAR2 (0.51) | HCAR2ALDH1A1ACLYALOX15TSHR | |
| SCHEMBL30474695 | 0.85 | HCAR2 (0.51) | HCAR2ALDH1A1ACLYALOX15TSHR | |
| SCHEMBL7974641 | 0.83 | ALDH1A1 (0.61) | NAMPTALDH1A1KDM4EPOLBALOX15 | |
| SCHEMBL7971906 | 0.82 | HTR6 (0.52) | HCAR2NAMPTALDH1A1L3MBTL1ACLY | |
| SCHEMBL31109019 | 0.81 | POLB (0.54) | HCAR2ALDH1A1KDM4EAPEX1POLB | |
| SCHEMBL31109098 | 0.81 | HCAR2 (0.54) | HCAR2NAMPTALDH1A1KDM4EAPEX1 | |
| SCHEMBL31109046 | 0.81 | HCAR2 (0.54) | HCAR2NAMPTALDH1A1KDM4EAPEX1 | |
| SCHEMBL6902193 | 0.79 | ALOX15 (0.71) | CHEK2ALDH1A1KDM4EALOX15TSHR | |
| SCHEMBL7958556 | 0.79 | NAMPT (0.45) | NAMPTALDH1A1KMT2ACA2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |