Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | S100A9 | P06702 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974641 | 0.87 | ALDH1A1 (0.61) | NAMPTALDH1A1CYP3A4MAPK1PTGS1 | |
| SCHEMBL7974709 | 0.83 | NAMPT (0.45) | NAMPTALDH1A1CYP3A4MAPK1PTGS1 | |
| SCHEMBL7969060 | 0.83 | GAA (0.55) | NAMPTALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL7971906 | 0.82 | HTR6 (0.52) | NAMPTALDH1A1CYP3A4MAPK1LMNA | |
| SCHEMBL7974869 | 0.79 | PKM (0.59) | NAMPTLMNAHTTPGRCA2 | |
| SCHEMBL7974711 | 0.79 | HCAR2 (0.54) | NAMPTALDH1A1MAPK1PTGS1PTGS2 | |
| SCHEMBL31109058 | 0.79 | HCAR2 (0.54) | NAMPTALDH1A1MAPK1PTGS1PTGS2 | |
| SCHEMBL4591070 | 0.77 | ALDH1A1 (0.76) | ALDH1A1CYP3A4MAPK1EGFRCCR2 | |
| SCHEMBL25900902 | 0.76 | LMNA (0.41) | NAMPTALDH1A1PTGS1PTGS2EGFR | |
| SCHEMBL710334 | 0.75 | PGR (0.61) | NAMPTALDH1A1CYP3A4MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |