Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NAMPT | P43490 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7958556 | 0.87 | NAMPT (0.45) | ALDH1A1MAPK1CYP3A4MEN1KMT2A | |
| SCHEMBL7969060 | 0.87 | GAA (0.55) | ALDH1A1MAPK1CYP3A4MEN1KMT2A | |
| SCHEMBL7974709 | 0.87 | NAMPT (0.45) | ALDH1A1MAPK1CYP3A4NAMPTPTGS1 | |
| SCHEMBL7971906 | 0.87 | HTR6 (0.52) | ALDH1A1MAPK1CYP3A4NAMPTHSD17B10 | |
| SCHEMBL7974869 | 0.83 | PKM (0.59) | NAMPTPKMSMN1; SMN2HTTLMNA | |
| SCHEMBL31109058 | 0.83 | HCAR2 (0.54) | ALDH1A1MAPK1MEN1KMT2ANAMPT | |
| SCHEMBL7974711 | 0.83 | HCAR2 (0.54) | ALDH1A1MAPK1MEN1KMT2ANAMPT | |
| SCHEMBL7974619 | 0.79 | AKR1B1 (0.47) | ALDH1A1CYP3A4NAMPTKDM4EHPGD | |
| SCHEMBL9313173 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4MEN1KMT2A | |
| SCHEMBL4328031 | 0.78 | ALDH1A1 (1.00) | ALDH1A1MAPK1CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |