Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974787 | 0.82 | TEAD1 (0.45) | MAOB | |
| SCHEMBL7961107 | 0.81 | MEN1 (0.44) | IDO1 | |
| SCHEMBL7961186 | 0.80 | HTR1A (0.43) | HTR1AADRA1DADRA1AADRA1BPDE4A | |
| SCHEMBL7971449 | 0.79 | MAOB (0.44) | MAOB | |
| SCHEMBL7974340 | 0.78 | CHRNB2 (0.44) | — | |
| SCHEMBL7971414 | 0.78 | PPARD (0.43) | MAOB | |
| SCHEMBL7974650 | 0.77 | MGAT2 (0.42) | MAOB | |
| SCHEMBL7974398 | 0.76 | MAOB (0.39) | MAOB | |
| SCHEMBL7974962 | 0.76 | MAOB (0.40) | MAOB | |
| SCHEMBL7961502 | 0.76 | MAOB (0.40) | GPR84MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |