Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 5/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972674 | 0.81 | MEN1 (0.49) | MEN1MAPTKMT2ADRD2DRD4 | |
| SCHEMBL7974758 | 0.81 | HTR1A (0.39) | IDO1 | |
| SCHEMBL7974787 | 0.78 | TEAD1 (0.45) | DRD2DRD4 | |
| SCHEMBL7971449 | 0.75 | MAOB (0.44) | MAPTDDB1CRBN | |
| SCHEMBL7971414 | 0.74 | PPARD (0.43) | — | |
| SCHEMBL7974650 | 0.73 | MGAT2 (0.42) | MEN1KMT2A | |
| SCHEMBL7974398 | 0.73 | MAOB (0.39) | DRD2DRD4DDB1CRBN | |
| SCHEMBL7974962 | 0.72 | MAOB (0.40) | — | |
| SCHEMBL7974340 | 0.72 | CHRNB2 (0.44) | DRD2 | |
| SCHEMBL7974454 | 0.71 | HRH3 (0.43) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |