Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | DHPS | P49366 | 2/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 8/20 | 0.34 |
| ▸ | FEN1 | P39748 | 7/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | DCK | P27707 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7985956 | 0.84 | MAPK14 (0.41) | MAPK14L3MBTL1ALOX5APFEN1TRPA1 | |
| SCHEMBL7989104 | 0.81 | PPP1CA (0.50) | MAPK14MAPK11BRDTL3MBTL1TDP1 | |
| SCHEMBL7989153 | 0.76 | ALDH1A1 (0.43) | L3MBTL1TDP1 | |
| SCHEMBL6406892 | 0.72 | MAPT (0.50) | MAPK14L3MBTL1ALOX5APFEN1 | |
| SCHEMBL7985834 | 0.69 | MEN1 (0.43) | MAPK14L3MBTL1BRD4 | |
| SCHEMBL7975567 | 0.69 | MAPK14 (0.49) | MAPK14L3MBTL1 | |
| SCHEMBL13529716 | 0.68 | DCK (0.53) | L3MBTL1TDP1DHPSALOX5APFEN1 | |
| SCHEMBL16569046 | 0.68 | KDM4E (0.35) | L3MBTL1 | |
| SCHEMBL7992031 | 0.66 | MAPK14 (0.41) | MAPK14L3MBTL1 | |
| SCHEMBL5619739 | 0.66 | L3MBTL1 (0.44) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | claimed |