Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | USP2 | O75604 | 8/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | CASP7 | P55210 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988190 | 0.90 | PDE10A (0.45) | USP2CYP1A2CYP3A4MEN1KMT2A | |
| SCHEMBL7985834 | 0.88 | MEN1 (0.43) | ALDH1A1MEN1KMT2ALTA4HSMN1; SMN2 | |
| SCHEMBL7986965 | 0.86 | MAPT (0.41) | ALDH1A1USP2CYP1A2CYP3A4MEN1 | |
| SCHEMBL7986045 | 0.82 | MEN1 (0.40) | MEN1KMT2ALTA4HL3MBTL1MAPT | |
| SCHEMBL7974674 | 0.81 | MEN1 (0.44) | ALDH1A1MEN1KMT2ATSHRLMNA | |
| SCHEMBL7974745 | 0.80 | MAPK14 (0.40) | MEN1KMT2AMAPK1 | |
| SCHEMBL7991980 | 0.77 | MAOB (0.51) | CYP1A2CYP2C19CYP2C9LMNASMN1; SMN2 | |
| SCHEMBL7974844 | 0.76 | MAPK14 (0.41) | L3MBTL1TDP1 | |
| SCHEMBL7989104 | 0.76 | PPP1CA (0.50) | ALDH1A1KMT2ATSHRSMN1; SMN2L3MBTL1 | |
| SCHEMBL16569046 | 0.72 | KDM4E (0.35) | ALDH1A1CYP1A2CYP3A4CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001032644-A2 | EXCITATORY AMINO ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-05-10 | — | — | WO | disclosed |