Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7988190 | 0.90 | PDE10A (0.45) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL7989153 | 0.88 | ALDH1A1 (0.43) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL7986045 | 0.85 | MEN1 (0.40) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL7974745 | 0.78 | MAPK14 (0.40) | MEN1KMT2AMAPK14 | |
| SCHEMBL7986965 | 0.77 | MAPT (0.41) | MEN1KMT2AHTTMAPTSMN1; SMN2 | |
| SCHEMBL7991980 | 0.77 | MAOB (0.51) | HTTSMN1; SMN2CYP11B1CYP11B2MAPK14 | |
| SCHEMBL5119715 | 0.76 | MEN1 (0.57) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL1415358 | 0.69 | MEN1 (0.50) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL5619272 | 0.69 | MEN1 (0.41) | MEN1KMT2AHTTMAPTL3MBTL1 | |
| SCHEMBL667593 | 0.68 | AURKA (0.57) | MEN1KMT2AHTTMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |