Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPP1CA | P62136 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | GAK | O14976 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKCH | P24723 | 1/20 | 0.35 |
| ▸ | PRKCI | P41743 | 1/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974844 | 0.81 | MAPK14 (0.41) | MAPK14L3MBTL1TDP1MAPK11BRDT | |
| SCHEMBL7985956 | 0.78 | MAPK14 (0.41) | KMT2AMAPK14L3MBTL1MAPTPDE10A | |
| SCHEMBL7989153 | 0.76 | ALDH1A1 (0.43) | KMT2AL3MBTL1MAPTGAAMAPK1 | |
| SCHEMBL19563690 | 0.73 | L3MBTL1 (0.56) | PPP1CAKMT2AL3MBTL1MAPTGAA | |
| SCHEMBL7986045 | 0.72 | MEN1 (0.40) | KMT2AMAPK14L3MBTL1MAPTPDE10A | |
| SCHEMBL7985834 | 0.69 | MEN1 (0.43) | KMT2AMAPK14L3MBTL1MAPTGAA | |
| SCHEMBL5119722 | 0.68 | DYRK1A (0.47) | MAPTGAAMAPK1NPSR1PDE4B | |
| SCHEMBL5619429 | 0.67 | L3MBTL1 (0.44) | PPP1CAKMT2AL3MBTL1MAPTGAA | |
| SCHEMBL7992858 | 0.67 | MAPK14 (0.40) | KMT2AMAPK14MAPTGAAMAPK1 | |
| SCHEMBL7539364 | 0.67 | MEN1 (0.49) | KMT2AMAPK14L3MBTL1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001042243-A2 | PROTEIN KINASE INHIBITORS | ADVANCED MEDICINE, INC. (US) | 2001-06-14 | — | — | WO | disclosed |