Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7993894 | 0.90 | RXFP1 (0.42) | RXFP1KDM4ENPC1RAB9AHPGD | |
| SCHEMBL7987577 | 0.77 | NPC1 (0.48) | KDM4ETDP1NPC1RAB9AHPGD | |
| SCHEMBL7975878 | 0.74 | TRPM8 (0.44) | KDM4ETDP1NPC1RAB9AHPGD | |
| SCHEMBL7993759 | 0.72 | MME (0.52) | KDM4ETDP1HPGD | |
| SCHEMBL7975974 | 0.71 | MAPK9 (0.49) | NPC1RAB9AHPGDSMN1; SMN2KMT2A | |
| SCHEMBL7993896 | 0.70 | TRPM8 (0.43) | HPGDTP53SMN1; SMN2MAPTKMT2A | |
| SCHEMBL7993650 | 0.70 | EDNRA (0.49) | NPC1RAB9AHPGDTP53SMN1; SMN2 | |
| SCHEMBL7976824 | 0.69 | HPGD (0.46) | KDM4ETDP1NPC1RAB9AHPGD | |
| SCHEMBL7986911 | 0.67 | EDNRA (0.47) | NPC1RAB9AHPGDTP53SMN1; SMN2 | |
| SCHEMBL11795717 | 0.67 | KDM4E (0.45) | KDM4ETDP1NPC1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207686-B1 | FOR THERAPY OF HYPERTENSION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-27 | — | — | US | disclosed |