Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.45 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 10/20 | 0.42 |
| ▸ | MMP8 | P22894 | 2/20 | 0.42 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 2/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989529 | 0.86 | MMP9 (0.52) | MMP9HRH4MMP2MMP8MME | |
| SCHEMBL7989539 | 0.86 | MMP9 (0.52) | MMP9HRH4MMP2MMP8MME | |
| SCHEMBL7993694 | 0.85 | MMP2 (0.54) | MMP9MMP2MMP8MMEACE | |
| SCHEMBL7986858 | 0.83 | MMP2 (0.46) | MMP2MMP1MMP3 | |
| SCHEMBL7986625 | 0.82 | MMP1 (0.38) | MMP2MMP1MMP3 | |
| SCHEMBL7986628 | 0.79 | MMP2 (0.42) | MMP2MMP8MMP1MMP3 | |
| SCHEMBL7990047 | 0.77 | PDF (0.50) | MMP2MMP1MMP3 | |
| SCHEMBL7987314 | 0.77 | MME (0.41) | MMP9MMP2MMEMMP1MMP3 | |
| SCHEMBL7977831 | 0.76 | MMP2 (0.44) | MMP9MMP2MMP8MMEACE | |
| SCHEMBL7977828 | 0.76 | MMP2 (0.44) | MMP9MMP2MMP8MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |