Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CCNC | P24863 | 3/20 | 0.43 |
| ▸ | CDK8 | P49336 | 3/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.42 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.42 |
| ▸ | ITGAL | P20701 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7982982 | 0.83 | FKBP1A (0.47) | MEN1KMT2ACCNCCDK8ALDH1A1 | |
| SCHEMBL7982986 | 0.83 | FKBP1A (0.47) | MEN1KMT2ACCNCCDK8ALDH1A1 | |
| SCHEMBL7966317 | 0.82 | MEN1 (0.44) | MEN1KMT2AAPPCCNCCDK8 | |
| SCHEMBL7966316 | 0.82 | MEN1 (0.44) | MEN1KMT2AAPPCCNCCDK8 | |
| SCHEMBL7966314 | 0.82 | MEN1 (0.44) | MEN1KMT2AAPPCCNCCDK8 | |
| SCHEMBL7976690 | 0.81 | USP2 (0.45) | RAB9ANPC1SMN1; SMN2MAPK1MEN1 | |
| SCHEMBL7966412 | 0.79 | USP2 (0.44) | SMN1; SMN2KMT2APOLBALDH1A1NAMPT | |
| Oxalic Acid SCHEMBL7978632 | 0.77 | MAPT (0.43) | RAB9AMEN1KMT2AKDM4EHPGD | |
| SCHEMBL7982583 | 0.74 | CYP1A2 (0.47) | SMN1; SMN2HPGDPOLBALDH1A1NAMPT | |
| SCHEMBL7982797 | 0.74 | CYP1A2 (0.47) | SMN1; SMN2HPGDPOLBALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |