Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PTAFR | P25105 | 8/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7976695 | 0.81 | RAB9A (0.46) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL7982982 | 0.79 | FKBP1A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7982986 | 0.79 | FKBP1A (0.47) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7966412 | 0.78 | USP2 (0.44) | USP2ALDH1A1SMN1; SMN2POLBKMT2A | |
| SCHEMBL7982583 | 0.74 | CYP1A2 (0.47) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2POLB | |
| SCHEMBL7982797 | 0.74 | CYP1A2 (0.47) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2POLB | |
| SCHEMBL7966316 | 0.73 | MEN1 (0.44) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL7966314 | 0.73 | MEN1 (0.44) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| SCHEMBL7966317 | 0.73 | MEN1 (0.44) | CYP1A1CYP1A2CYP3A4CYP2D6CYP1B1 | |
| Oxalic Acid SCHEMBL7978632 | 0.71 | MAPT (0.43) | ALDH1A1MAPTRAB9AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300352-B1 | FOR THERAPY OF ASTHMA | ASTRAZENECA AB (SE) | 2001-10-09 | — | — | US | disclosed |