Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10791 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL103468 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL12367675 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL2677860 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL12802471 | 0.73 | — | — | |
| SCHEMBL8951223 | 0.73 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL1259792 | 0.72 | L3MBTL1 (0.38) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL7932103 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL8035901 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 | |
| SCHEMBL965723 | 0.72 | ALDH1A1 (0.48) | ALDH1A1HPGDMMP1MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |