Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.52 |
| ▸ | HPGD | P15428 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7998201 | 0.88 | ALDH1A1 (0.51) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7983893 | 0.81 | ALDH1A1 (0.50) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7994239 | 0.77 | CYP1A2 (0.49) | ALDH1A1HPGDKDM4EHSD17B10MAPT | |
| SCHEMBL7963947 | 0.76 | RAB9A (0.70) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL7977530 | 0.73 | HSD17B10 (0.54) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL12503286 | 0.69 | FKBP1A (0.71) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL2240977 | 0.69 | KMT2A (0.50) | ALDH1A1HPGDKDM4ELMNAHTT | |
| SCHEMBL7994077 | 0.69 | PDCD1 (0.46) | ALDH1A1HPGDTSHRKDM4EHSD17B10 | |
| SCHEMBL24273653 | 0.67 | CYP1A2 (0.79) | ALDH1A1HPGDTSHRKDM4EMAPT | |
| SCHEMBL16957698 | 0.66 | PDCD1 (0.50) | ALDH1A1L3MBTL1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034578-A1 | COMPOUNDS WITH ANTI-HELICOBACTER PYLORI ACTIVITY | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |