Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | BDKRB1 | P46663 | 3/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984066 | 0.84 | POLB (0.44) | SMN1; SMN2KDM4EMEN1KMT2APOLB | |
| SCHEMBL11006059 | 0.79 | SMN1; SMN2 (0.39) | NR3C2SMN1; SMN2KDM4ENPC1RAB9A | |
| SCHEMBL7983845 | 0.76 | LMNA (0.50) | SMN1; SMN2KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL11015788 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4EPDE3BPDE3ANPC1 | |
| SCHEMBL11009673 | 0.73 | ALDH1A1 (0.55) | SMN1; SMN2KDM4EMEN1KMT2A | |
| SCHEMBL8600882 | 0.72 | CACNB4 (0.43) | SMN1; SMN2KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL10730613 | 0.72 | SMN1; SMN2 (0.52) | NR3C2SMN1; SMN2AKT1KDM4ENPC1 | |
| SCHEMBL8805653 | 0.68 | CYP1A2 (0.46) | SMN1; SMN2KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL10748490 | 0.67 | TDP2 (0.38) | SMN1; SMN2KDM4ENPC1RAB9AMEN1 | |
| SCHEMBL7979537 | 0.67 | POLB (0.44) | NR3C2SMN1; SMN2KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6194428-B1 | BRAIN DISORDERS; PSYCHOLOGICAL DISORDERS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-02-27 | — | — | US | claimed |