Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.33 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6324712 | 0.79 | HSD17B10 (0.40) | HSD17B10PARP1 | |
| SCHEMBL9305475 | 0.79 | KIF11 (0.39) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL11808209 | 0.78 | KIF11 (0.38) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL13080216 | 0.76 | KIF11 (0.42) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10707110 | 0.76 | CNR1 (0.37) | KDM4EMAPTKMT2ALMNANPC1 | |
| SCHEMBL4976888 | 0.76 | KDM4E (0.31) | KDM4EMAPTMEN1KMT2APOLB | |
| SCHEMBL21708439 | 0.75 | MAOA (0.40) | ALDH1A1MEN1KMT2APOLBSMN1; SMN2 | |
| SCHEMBL8083834 | 0.74 | TUBB4A (0.43) | LMNATSHR | |
| SCHEMBL6608676 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10846158 | 0.73 | ATP4A (0.36) | KDM4EALDH1A1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001034573-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2001-05-17 | — | — | WO | disclosed |