SCHEMBL21708439

SCHEMBL21708439

COCc1ccc2[nH]c(S)nc2c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.40
DYRK1A Q13627 1/20 0.40
TP53 P04637 2/20 0.34
POLB P06746 2/20 0.34
LMNA P02545 1/20 0.34
CA2 P00918 1/20 0.33
SYK P43405 1/20 0.32
SLC2A1 P11166 1/20 0.32
NPC1 O15118 4/20 0.31
RAB9A P51151 4/20 0.31
SMN1; SMN2 Q16637 4/20 0.31
MEN1 O00255 1/20 0.31
NFKB1 P19838 1/20 0.31
NFKB2 Q00653 1/20 0.31
KMT2A Q03164 1/20 0.31
RELA Q04206 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PDE10A Q9Y233 1/20 0.30
CBFB Q13951 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9305475 0.81 KIF11 (0.39) TP53LMNANPC1RAB9ASMN1; SMN2
SCHEMBL11808209 0.80 KIF11 (0.38) TP53LMNANPC1RAB9ASMN1; SMN2
SCHEMBL10707110 0.79 CNR1 (0.37) LMNANPC1RAB9AKMT2A
SCHEMBL6324712 0.78 HSD17B10 (0.40) MAOADYRK1ACBFB
SCHEMBL4976888 0.78 KDM4E (0.31) POLBRAB9ASMN1; SMN2MEN1KMT2A
SCHEMBL8083834 0.76 TUBB4A (0.43) LMNA
SCHEMBL10846158 0.75 ATP4A (0.36) TP53LMNANPC1RAB9ASMN1; SMN2
SCHEMBL13438570 0.75 SLC2A1 (0.42) LMNASLC2A1ALDH1A1CBFB
SCHEMBL7977592 0.75 KDM4E (0.38) POLBLMNANPC1RAB9ASMN1; SMN2
SCHEMBL916531 0.75 ALDH1A1 (0.48) TP53POLBLMNANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11733608-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-22 US disclosed
US-11720018-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-08-08 US disclosed
US-20220004101-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-01-06 US disclosed
US-11204553-B2 Chemically amplified resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-12-21 US disclosed
US-20210294211-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-09-23 US disclosed
US-20210048747-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-18 US disclosed
US-20210033969-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-02-04 US disclosed
US-20200192222-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-06-18 US disclosed
US-20200050104-A1 CHEMICALLY AMPLIFIED RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2020-02-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210294211-A1 RESIST COMPOSITION AND PATTERNING PROCESS HNRNPU, INSR, BICRA MAOA 3471/4885DYRK1A 18/4885TP53 3060/4885
US-11733608-B2 Resist composition and patterning process HNRNPU, INSR, BICRA MAOA 3471/4885DYRK1A 18/4885TP53 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.