Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 5/20 | 0.47 |
| ▸ | TGM2 | P21980 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7975562 | 1.00 | FOLH1 (0.47) | FOLH1TGM2PTGER4SIRT2CPB1 | |
| SCHEMBL7989516 | 0.84 | MMP3 (0.42) | FOLH1 | |
| SCHEMBL7986858 | 0.81 | MMP2 (0.46) | — | |
| SCHEMBL7977831 | 0.81 | MMP2 (0.44) | — | |
| SCHEMBL7977828 | 0.81 | MMP2 (0.44) | — | |
| SCHEMBL7987530 | 0.77 | MMP3 (0.37) | — | |
| SCHEMBL24130652 | 0.75 | FOLH1 (0.60) | FOLH1SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL24130242 | 0.75 | FOLH1 (0.60) | FOLH1SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL7990047 | 0.75 | PDF (0.50) | — | |
| SCHEMBL7985989 | 0.74 | FFAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |