Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 3/20 | 0.37 |
| ▸ | EPOR | P19235 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7989433 | 0.87 | KDM4E (0.43) | KDM4ENPC1ALDH1A1RAB9AALOX5 | |
| SCHEMBL7987530 | 0.83 | MMP3 (0.37) | — | |
| SCHEMBL7977831 | 0.83 | MMP2 (0.44) | MAOB | |
| SCHEMBL7977828 | 0.83 | MMP2 (0.44) | MAOB | |
| SCHEMBL7986860 | 0.78 | MMP2 (0.38) | — | |
| SCHEMBL7987529 | 0.76 | MMP3 (0.42) | — | |
| SCHEMBL7989516 | 0.76 | MMP3 (0.42) | — | |
| SCHEMBL7993697 | 0.74 | KMT2A (0.40) | FFAR1ALDH1A1 | |
| SCHEMBL7986630 | 0.74 | TAAR1 (0.33) | ALDH1A1ALOX5 | |
| SCHEMBL7975565 | 0.74 | FOLH1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001040198-A2 | MACROCYCLIC HYDROXAMIC ACID DERIVATIVES AND THEIR USE AS ANTIMICROBIAL AGENTS | AVENTIS PHARMA S.A. (FR) | 2001-06-07 | — | — | WO | disclosed |