Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.51 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.51 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.51 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617262 | 0.91 | SIGMAR1 (0.48) | CARM1PRMT6PRMT3PRMT1PRMT8 | |
| SCHEMBL1808554 | 0.85 | DRD2 (0.54) | CARM1PRMT6SLC6A2SLC6A4CHRM1 | |
| SCHEMBL6622326 | 0.79 | SIGMAR1 (0.39) | SIGMAR1CYP2D6CHRM3 | |
| SCHEMBL7978211 | 0.78 | KDM1A (0.59) | HTT | |
| SCHEMBL7754129 | 0.76 | CARM1 (0.55) | CARM1PRMT6PRMT3PRMT1PRMT8 | |
| SCHEMBL15702621 | 0.74 | BCHE (0.61) | SLC6A2SLC6A4CHRM1SLC6A3SIGMAR1 | |
| SCHEMBL24076360 | 0.74 | HTR2A (0.71) | CARM1PRMT6PRMT3PRMT1PRMT8 | |
| SCHEMBL15702652 | 0.73 | ACHE (0.62) | SLC6A2SLC6A4SLC6A3BACE1 | |
| SCHEMBL7978284 | 0.73 | CARM1 (0.51) | CARM1PRMT6PRMT3PRMT1PRMT8 | |
| SCHEMBL7976350 | 0.73 | CHRM2 (0.65) | CARM1PRMT6PRMT3PRMT1PRMT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255323-B1 | Cyanoguanidine compounds | SHIONOGI BIORESEARCH CORP. | 2001-07-03 | — | — | US | disclosed |
| WO-2000061561-A1 | CYANOGUANIDINE COMPOUNDS | SHIONOGI BIORESEARCH CORP. (US) | 2000-10-19 | — | — | WO | disclosed |