Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7978255 | 0.85 | CARM1 (0.51) | SLC6A4CHRM1SLC6A2CARM1PRMT6 | |
| SCHEMBL6617262 | 0.82 | SIGMAR1 (0.48) | SLC6A4CHRM1SLC6A2CARM1PRMT6 | |
| SCHEMBL4499136 | 0.81 | OPRD1 (0.53) | — | |
| SCHEMBL1807864 | 0.81 | DRD2 (0.53) | DRD2SLC6A4SLC6A2CARM1PRMT6 | |
| SCHEMBL27576810 | 0.81 | CHRM1 (0.44) | SLC6A4CHRM1SLC6A2CARM1PRMT6 | |
| SCHEMBL7978211 | 0.78 | KDM1A (0.59) | DRD2ACHE | |
| SCHEMBL14198387 | 0.78 | DRD2 (0.60) | DRD2SLC6A4CARM1PRMT6SIGMAR1 | |
| SCHEMBL15702621 | 0.77 | BCHE (0.61) | SLC6A4CHRM1SLC6A2ACHESIGMAR1 | |
| SCHEMBL6175328 | 0.76 | CARM1 (0.72) | DRD2SLC6A4CARM1PRMT6SIGMAR1 | |
| SCHEMBL15702652 | 0.76 | ACHE (0.62) | SLC6A4SLC6A2ACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |
| WO-2011060271-A1 | SCREENING FOR INHIBITORS OF P. FALCIPARUM USING LUCIFERASE BASED HIGH THROUGHPUT SCREENING ASSAY | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2011-05-19 | — | — | WO | disclosed |